SHAM (n = 38) | Gondola® (n = 36) | SHAM (n = 38) | Gondola® (n = 36) | SHAM (n = 38) | Gondola® (n = 36) | p value | ||
---|---|---|---|---|---|---|---|---|
T1 | T2 | T2 vsT1 | ||||||
Primary outcome | ||||||||
Velocity [m/s] | 0.62 ± 0.19 | 0.68 ± 0.21 | 0.66 ± 0.21 | 0.87 ± 0.24 | 0.04 ± 0.13 | 0.19 ± 0.21 | < 0.001 | |
Secondary outcomes | ||||||||
Spatiotemporal parameters of gait analysis | Cadence [stride/min] | 103.15 ± 15.33 | 103.04 ± 14.60 | 103.95 ± 15.66 | 107.48 ± 13.79 | 0.79 ± 16.97 | 4.44 ± 9.74 | 0.271 |
Stride length [m] | 0.75 ± 0.23 | 0.80 ± 0.22 | 0.78 ± 0.22 | 0.98 ± 0.23 | 0.03 ± 0.17 | 0.18 ± 0.22 | 0.002 | |
% Stride length | 46.46 ± 14.03 | 49.07 ± 12.49 | 48.32 ± 13.81 | 59.84 ± 12.06 | 1.86 ± 10.42 | 10.77 ± 13.58 | 0.003 | |
Stride duration [s] | 1.21 ± 0.16 | 1.21 ± 0.19 | 1.20 ± 0.18 | 1.15 ± 0.21 | − 0.012 ± 0.18 | − 0.059 ± 0.12 | 0.212 | |
Stance phase [%] | 61.94 ± 2.53 | 61.54 ± 2.76 | 61.57 ± 2.61 | 60.87 ± 2.60 | − 0.376 ± 2.91 | − 0.672 ± 2.78 | 0.660 | |
Swing phase [%] | 38.05 ± 2.53 | 38.46 ± 2.76 | 38.43 ± 2.61 | 39.13 ± 2.60 | 0.376 ± 2.91 | 0.672 ± 2.78 | 0.660 | |
Initial phase of double support [%] | 11.83 ± 2.59 | 11.54 ± 2.75 | 11.40 ± 2.62 | 10.84 ± 2.48 | − 0.424 ± 2.97 | − 0.70 ± 2.85 | 0.687 | |
Single support phase [%] | 38.21 ± 2.66 | 38.44 ± 2.73 | 38.54 ± 2.61 | 39.17 ± 2.53 | 0.336 ± 2.94 | 0.732 ± 2.81 | 0.562 | |
Propulsion [m/s2] | 3.76 ± 1.34 | 3.85 ± 1.33 | 3.81 ± 1.43 | 4.64 ± 1.43 | 0.045 ± 1.11 | 0.793 ± 1.51 | 0.019 | |
Functional motor assessments | FOG-Q (0–24) | 10.62 ± 4.80 | 11.76 ± 4.69 | 10.52 ± 4.73 | 10.32 ± 4.46 | − 0.11 ± 1.52 | − 1.44 ± 2.27 | 0.005 |
TUG [s] | 22.40 ± 8.36 | 25.54 ± 17.11 | 22.94 ± 10.24 | 22.60 ± 24.92 | 0.54 ± 6.72 | − 2.94 ± 11.59 | 0.121 | |
TUG Dual-task [s] | 28.97 ± 11.94 | 39.71 ± 53.49 | 31.97 ± 16.44 | 35.86 ± 55.22 | 3.00 ± 13.15 | − 3.85 ± 20.96 | 0.099 | |
Mini-BESTest (0–28) | 14.83 ± 5.21 | 15.34 ± 4.46 | 14.76 ± 4.98 | 16.14 ± 4.42 | − 0.08 ± 1.23 | 0.80 ± 1.54 | 0.009 | |
MDS-UPDRS | ||||||||
− 2.12 | 1.73 ± 0.92 | 1.83 ± 0.89 | 1.67 ± 0.94 | 1.65 ± 0.87 | − 0.05 ± 0.57 | − 0.17 ± 0.51 | 0.365 | |
− 2.13 | 1.32 ± 1.04 | 1.60 ± 1.00 | 1.29 ± 1.02 | 1.34 ± 1.00 | − 0.027 ± 0.50 | − 0.26 ± 0.61 | 0.084 | |
− 3.10 | 2.19 ± 0.83 | 2.03 ± 0.77 | 2.16 ± 0.87 | 1.67 ± 0.76 | − 0.027 ± 0.37 | − 0.36 ± 0.60 | 0.006 | |
− 3.11 | 1.35 ± 1.25 | 1.36 ± 1.06 | 1.35 ± 1.18 | 1.00 ± 0.98 | 0.01 ± 0.47 | − 0.36 ± 0.65 | 0.009 | |
− 3.12 | 2.00 ± 1.00 | 2.03 ± 1.12 | 2.13 ± 1.03 | 1.67 ± 1.21 | 0.13 ± 0.42 | − 0.36 ± 0.49 | < 0.001 |