Skip to main content

Table 4 Analyses of the motor evoked potentials (MEPs): threshold, peak-to-peak and latencies of quadriceps rectus femoris (RF) and tibialis anterior (TA). Confidence interval (CI)

From: Transcutaneous spinal cord stimulation combined with robotic-assisted body weight-supported treadmill training enhances motor score and gait recovery in incomplete spinal cord injury: a double-blind randomized controlled clinical trial

Outcomes

Muscle

Assessment

Intervention group (tSCS + Lokomat)

Control Group (sham tSCS + Lokomat)

Comparison of changes

Intervention vs. control

Mean difference (95% CI)

Mean (SD)

Change score

Mean (SD)

Change score

Post

Baseline-Follow

Threshold (%)

RF

Pre-

53.64 (20.60)

− 3.18 (13.63)$

49.90 (9.93)

− 1.30 (2.16)$

− 1.88 (− 11.031 to 7.26)&

− 4.45 (− 13.39 to 4.48)&

Post-

50.45 (13.23)

48.60 (9.36)

Follow-up

49.18 (12.27)

− 4.45 (12.34)$

49.90 (10.00)

0.00 (5.71)$

TA

Pre-

43.82 (9.80)

0.63 (4.80)$

47.22 (10.03)

− 0.44 (2.13)$

− 1.08 (− 2.55 to 4.71)&

1.45 (− 1.98 to 4.89)&

Post-

44.45 (9.47)

46.78 (9.87)

Follow-up

44.27 (9.10)

0.45 (4.08)$

46.22 (10.23)

− 1.00 (3.00)$

Peak-to-peak

Amplitude (mV)

RF

Pre-

4.77 (2.44)

− 0.16 (1.67)*

7.17 (3.02)

− 0.90 (3.72)*

0.75 (− 2.39 to 3.90)

2.40 (0.00 to 4.80)

p < 0.05

 

Post-

4.61 (1.38)

6.27 (3.41)

 

Follow-up

3.79 (0.85)

− 0.97 (1.82)*

3.78 (1.49)

− 3.39 (2.34)*

p < 0.01

TA

Pre-

14.76 (7.81)

2.22 (7.45)$

14.69 (16.39)

0.40 (3.60)$

1.82 (− 9.76 to 6.12)&

− 7.26 (− 26.76 to 12.24)&

 

Post-

16.98 (8.29)

15.09 (16.18)

 

Follow-up

22.03 (22.72)

7.27 (18.26)$

14.70 (10.78)

0.01 (8.97)$

Latency (ms)

RF

Pre-

33.38 (5.31)

− 1.31 (3.29)*

32.43 (3.97)

2.59 (2.92)*

− 3.92 (− 7.66 to − 0.17)

p < 0.05

− 1.95 (− 7.49 to 3.58)

Post-

32.12 (4.67)

35.02 (4.40)

Follow-up

31.71 (4.39)

− 1.67(3.80)*

32.44 (5.23)

0.01 (5.80)*

TA

Pre-

46.43 (7.36)

− 3.08 (4.20)*

46.68 (13.87)

7.45 (30.45)*

− 10.53 (− 31.10 to 9.50)

1.40 (− 6.62 to 9.42)

Post-

43.36 (6.39)

54,13 (18.41)

Follow-up

43.76 (5.29)

− 2.67 (3.93)*

42.48 (7.82)

− 4.20 (10.66)*

  1. One-way repeated ANOVA and post-hoc Bonferroni (*); Friedmann test and Wilcoxon post-hoc ($). Intergroup comparison changes scores with t-student independent samples () and Mann–Whitney-U test (&). Bold font indicates statistical significance (p < 0.05)